Volume EM Alignment Service

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Raw image acquisition by Francis Crick Institute

3D Alignment and Registration

Proper alignment of 3D electron microscopy image stacks is crucial for effective manual and automatic analysis. Overlapping regions are stitched together into a coherent dataset.
We offer a full service for the alignment of 3D electron microscopy datasets. Just upload the dataset and receive the results. No coding required.

2D In-Plane Stitching and Montages

Easily combine individual image tiles produced by your microscope into a single plane. Overlapping regions are stitched together with smart outlier rejection.
We offer a full service for the alignment of large-scale 2D electron microscopy or other images. Just upload the dataset and receive the results. No coding required.

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Raw image acquisition by Carles Bosch, Francis Crick Institute

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Raw image acquisition by Max Planck Institute for Brain Research

Normalization and Gradient Correction

Due to the sensitive nature of image acquisition, some artifacts are inevitable. Sections may show uneven brightness and contrast. There may be gradients across tiles or throughout the dataset.
Fortunately, these artifacts can be corrected using our technology. As part of our alignment and stitching services or separately, we offer services for normalization and gradient correction in large-scale datasets. 

Stitching of 3D Tiles

Imaging large volumes with Micro-CT or Synchrotron X-Ray Tomography requires sub-dividing the volume into 3D tiles.
We offer services for stitching reconstructed tomography tiles into a coherent dataset.

Raw image data by Carles Bosch, Francis Crick Institute